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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ELK-ES1040.50 | 50 µl | - | - |
Request delivery time estimate |
169.00€
|
||
ELK-ES1040.100 | 100 µl | - | - |
Request delivery time estimate |
283.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing... more
Product information "Anti-cleaved-KLK8 (Val33)"
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in tandem in a gene cluster on chromosome 19. The encoded protein may be involved in proteolytic cascade in the skin and may serve as a biomarker for ovarian cancer. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013], Protein function: Serine protease which is capable of degrading a number of proteins such as casein, fibrinogen, kininogen, fibronectin and collagen type IV. Also cleaves L1CAM in response to increased neural activity. Induces neurite outgrowth and fasciculation of cultured hippocampal neurons. Plays a role in the formation and maturation of orphan and small synaptic boutons in the Schaffer-collateral pathway, regulates Schaffer-collateral long-term potentiation in the hippocampus and is required for memory acquisition and synaptic plasticity. Involved in skin desquamation and keratinocyte proliferation. Plays a role in the secondary phase of pathogenesis following spinal cord injury. [The UniProt Consortium] Recommended dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.. Cellular localization: Secreted . Cytoplasm . Shows a cytoplasmic distribution in the keratinocytes.
Keywords: | Anti-cleaved-NP, Anti-cleaved-hK8, Anti-cleaved-NRPN, Anti-cleaved-KLK8, Anti-cleaved-Ovasin, Anti-cleaved-Neuropsin, Anti-cleaved-Kallikrein-8, EC=3.4.21.118, Anti-cleaved-Serine protease 19, Anti-cleaved-Serine protease TADG-14, Anti-cleaved-Tumor-assoc |
Supplier: | ELK Biotechnology |
Supplier-Nr: | ES1040 |
Properties
Application: | WB, ELISA |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, rat, mouse, |
Immunogen: | The antiserum was produced against synthesized peptide derived from human Neuropsin. AA range:14-63 |
MW: | 24 kD |
Format: | Antiserum |
Database Information
KEGG ID : | K08650 | Matching products |
UniProt ID : | O60259 | Matching products |
Gene ID | GeneID 11202 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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