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Item number: AG-20B-0020-C100
Recognizes the posttranslational modification (poly)glutamylation on proteins. Reacts with polyglutamylated alpha- and beta-tubulin. Liquid. In PBS containing 10% glycerol and 0.02% sodium azide. Polyglutamylation is a post-translational modification in which glutamate side chains of variable lengths are formed on...
Keywords: | Polyglutamylated Tubulin, Glutamylated Tubulin, Postranslational Protein Glutamylation |
Application: | ICC, IP, WB, IHC (paraffin), IEM |
Host: | Mouse |
Species reactivity: | All |
451.00€
*
Item number: A300-245A
Protein function: As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA...
Keywords: | Anti-phospho-RPA2, Anti-phospho-REPA2, Anti-phospho-RP-A p34, Anti-phospho-RP-A p32, Anti-phospho-RF-A protein 2,... |
Application: | WB, IP, IHC, ICC-IF |
Host: | Rabbit |
Species reactivity: | human, mouse |
From 164.00€
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Item number: A300-246A
Protein function: As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA...
Keywords: | Anti-phospho-RPA2, Anti-phospho-REPA2, Anti-phospho-RP-A p34, Anti-phospho-RP-A p32, Anti-phospho-RF-A protein 2,... |
Application: | WB |
Host: | Rabbit |
Species reactivity: | human |
From 164.00€
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Item number: A300-767A
Protein function: Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of...
Keywords: | Anti-phospho-KAP1, Anti-phospho-KAP-1, Anti-phospho-TRIM28, Anti-phospho-KRIP-1, Anti-phospho-TIF1-beta, EC=6.3.2.-,... |
Application: | WB, IP, IHC, ICC, ICC-IF |
Host: | Rabbit |
Species reactivity: | human, mouse |
From 164.00€
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Item number: 200-301-400
Protein function: Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]-Q. Phosphorylates 'Ser-139' of...
Keywords: | Anti-phospho-ATM, Anti-phospho-A-T mutated, EC=2.7.11.1, Anti-phospho-Serine-protein kinase ATM, Anti-phospho-Ataxia... |
Application: | ELISA, FC, IHC, IFM, WB |
Host: | Mouse |
Species reactivity: | human, mouse, rat |
From 180.00€
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Item number: 0047-100
Does not cross-react with the non-phosphorylated form of VASP nor with unrelated serine-phosphorylated proteins.
Keywords: | (pS239) Anti-phospho-VASP, Anti-phospho-VASP, Anti-phospho-Vasodilator-stimulated phosphoprotein |
Application: | WB, ELISA, IP, ICC, FC |
Host: | Mouse |
Species reactivity: | human, mouse |
428.00€
*
Item number: A300-654A
Protein function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Largest and catalytic component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Forms the polymerase active center together...
Keywords: | Anti-phospho-POLR2, Anti-phospho-POLR2A, EC=2.7.7.6, EC=2.7.7.48, Anti-phospho-RNA polymerase II subunit B1,... |
Application: | WB, IP, IHC |
Host: | Rabbit |
Species reactivity: | human, mouse |
From 164.00€
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Item number: A300-081A
Protein function: Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA...
Keywords: | Anti-H2AX, Anti-H2AFX, Anti-H2a/x, Anti-Histone H2AX, Anti-Histone H2A.X |
Application: | WB, IHC, ICC-IF |
Host: | Rabbit |
Species reactivity: | human, mouse |
From 164.00€
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Item number: A300-003A-T
BRCA1 was identified as a gene with germline mutations that predisposes women to breast and ovarian cancer. The BRCA1 tumor suppressor is a large protein that has been demonstrated to interact with a multitude of proteins involved in the DNA damage response and cell cycle checkpoints to maintain genomic integrity....
Keywords: | Anti-phospho-BRCA1, Anti-phospho-RNF53, Anti-phospho-RING finger protein 53, Anti-phospho-RING-type E3 ubiquitin... |
Application: | WB |
Host: | Rabbit |
Species reactivity: | human |
164.00€
*
Item number: A300-004A-T
BRCA1 was identified as a gene with germline mutations that predisposes women to breast and ovarian cancer. The BRCA1 tumor suppressor is a large protein that has been demonstrated to interact with a multitude of proteins involved in the DNA damage response and cell cycle checkpoints to maintain genomic integrity....
Keywords: | Anti-phospho-BRCA1, Anti-phospho-RNF53, Anti-phospho-RING finger protein 53, Anti-phospho-RING-type E3 ubiquitin... |
Application: | WB, IP |
Host: | Rabbit |
Species reactivity: | human |
164.00€
*
Item number: A300-059A-T
X-ray repair cross-complementing protein 1 (XRCC1) has been identified as a gene that partially rescues a DNA repair defect and therefore plays a role in efficient repair of single-stranded breaks in DNA damage caused by ionizing radiation. XRCC1 interacts with human polynucleotide kinase, DNA polymerase-beta, and...
Keywords: | Anti-phospho-X-ray repair cross complementing protein 1 variant |
Application: | WB, IHC |
Host: | Rabbit |
Species reactivity: | human |
164.00€
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Item number: A300-147A-T
X-ray repair cross-complementing protein 1 (XRCC1) has been identified as a gene that partially rescues a DNA repair defect and therefore plays a role in efficient repair of single-stranded breaks in DNA damage caused by ionizing radiation. XRCC1 interacts with human polynucleotide kinase, DNA polymerase-beta, and...
Keywords: | Anti-phospho-X-ray repair cross complementing protein 1 variant |
Application: | WB, IHC |
Host: | Rabbit |
Species reactivity: | human |
164.00€
*