Anti-ZYG11B

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA028156.25	25 µl		-		7 - 10 business days*		335.00€
ATA-HPA028156.100	100 µl		-		7 - 10 business days*		446.00€

If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk

Protein function: Serves as substrate adapter subunit in the E3 ubiquitin ligase complex... more

Close menu

Product information "Anti-ZYG11B"

Protein function: Serves as substrate adapter subunit in the E3 ubiquitin ligase complex ZYG11B-CUL2-Elongin BC. Acts redudantly with ZER1 to target substrates bearing N-terminal glycine degrons for proteasomal degradation (PubMed:33093214). Involved in the clearance of proteolytic fragments generated by caspase cleavage during apoptosis since N- terminal glycine degrons are strongly enriched at caspase cleavage sites. Also important in the quality control of protein N- myristoylation in which N-terminal glycine degrons are conditionally exposed after a failure of N-myristoylation (PubMed:31273098). [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 100% and to rat: 100%

Keywords:	Anti-KIAA1730, Anti-Protein zyg-11 homolog B
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA028156

Properties

Application:	ICC, IHC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: DATGVNADIT ITDIISGLGS NKWIQQNLQC LVLNSLTLSL EDPYERCFSR LSGLRALSIT NVLFYNEDLA EVASLPRLES LDISNTSI (ATA-APrEST76956)