Anti-ZRAN1

Anti-ZRAN1
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ELK-ES12076.50 50 µl - -

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169.00€
ELK-ES12076.100 100 µl - -

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283.00€
 
Protein function: Ubiquitin thioesterase, which specifically hydrolyzes 'Lys- 29'-linked and... more
Product information "Anti-ZRAN1"
Protein function: Ubiquitin thioesterase, which specifically hydrolyzes 'Lys- 29'-linked and 'Lys-33'-linked diubiquitin (PubMed:22157957, PubMed:23827681, PubMed:25752573, PubMed:25752577). Also cleaves 'Lys- 63'-linked chains, but with 40-fold less efficiency compared to 'Lys- 29'-linked ones (PubMed:18281465). Positive regulator of the Wnt signaling pathway that deubiquitinates APC protein, a negative regulator of Wnt-mediated transcription (PubMed:18281465). Acts as a regulator of autophagy by mediating deubiquitination of PIK3C3/VPS34, thereby promoting autophagosome maturation (PubMed:33637724). Plays a role in the regulation of cell morphology and cytoskeletal organization (PubMed:21834987). Required in the stress fiber dynamics and cell migration (PubMed:21834987). [The UniProt Consortium] Recommended dilutions: WB 1:500-2000. Cellular localization: Cytoplasm . Nucleus . Enriched in punctate localization in the cytoplasm. .
Keywords: Anti-hTrabid, Anti-Ubiquitin thioesterase ZRANB1, Anti-TRAF-binding domain-containing protein, Anti-Zinc finger Ran-binding domain-containing protein 1, ZRAN1 rabbit pAb
Supplier: ELK Biotechnology
Supplier-Nr: ES12076

Properties

Application: WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse
Immunogen: Synthesized peptide derived from human ZRAN1 AA range: 255-305
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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