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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| ELK-ES18896.50 | 50 µl | - | - |
Request delivery time estimate |
169.00€
|
||
| ELK-ES18896.100 | 100 µl | - | - |
Request delivery time estimate |
283.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Transcription factor that binds to the sequence motif 5'- CATCCCATAATA-3', and... more
Product information "Anti-ZN410"
Protein function: Transcription factor that binds to the sequence motif 5'- CATCCCATAATA-3', and is specifically required to silence expression of fetal hemoglobin in adult erythroid cells (PubMed:33859416, PubMed:33301730). Prevents expression of fetal hemoglobin genes HBG1 and HBG2 through CHD4: acts as a direct transcriptional activator of CHD4, a central component of the NuRD complex that represses transcription of fetal hemoglobin genes HBG1 and HBG2 in erythroid cells (PubMed:33859416, PubMed:33301730). May also activate transcription of matrix-remodeling genes such as MMP1 during fibroblast senescence (PubMed:12370286). May activate transcription of the gap junction gene GJC1, perhaps in response to increasing glucose (PubMed:30078215). However, recent studies suggest that ZNF410 is dedicated to regulate expression of a single gene: CHD4 (PubMed:33859416, PubMed:33301730). [The UniProt Consortium] Recommended dilutions: WB 1:1000-2000. Cellular localization: Nucleus . Chromosome . Directly binds to the sequence motif 5'-CATCCCATAATA-3'. .
| Keywords: | Anti-Zinc finger protein 410, Anti-Another partner for ARF 1, ZN410 rabbit pAb |
| Supplier: | ELK Biotechnology |
| Supplier-Nr: | ES18896 |
Properties
| Application: | WB |
| Antibody Type: | Polyclonal |
| Conjugate: | No |
| Host: | Rabbit |
| Species reactivity: | human, mouse |
| Immunogen: | Synthesized peptide derived from human ZN410 AA range: 113-163 |
| Format: | Purified |
Database Information
| KEGG ID : | K25858 | Matching products |
| UniProt ID : | Q86VK4 | Matching products |
| Gene ID | GeneID 57862 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
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