Anti-ZER1

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA048464.25	25 µl		-		7 - 10 business days*		335.00€
ATA-HPA048464.100	100 µl		-		7 - 10 business days*		446.00€

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Protein function: Serves as substrate adapter subunit in the E3 ubiquitin ligase complex... more

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Product information "Anti-ZER1"

Protein function: Serves as substrate adapter subunit in the E3 ubiquitin ligase complex ZYG11B-CUL2-Elongin BC (PubMed:17304241, PubMed:31273098). Acts redudantly with ZYG11B to target substrates bearing N-terminal glycine degrons for proteasomal degradation (PubMed:33093214). Involved in the clearance of proteolytic fragments generated by caspase cleavage during apoptosis since N-terminal glycine degrons are strongly enriched at caspase cleavage sites. Also important in the quality control of protein N-myristoylation in which N-terminal glycine degrons are conditionally exposed after a failure of N- myristoylation (PubMed:31273098). [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 98% and to rat: 98%

Keywords:	Anti-Hzyg, Anti-C9orf60, Anti-Zyg11b-like protein, Anti-Protein zer-1 homolog, Anti-Zyg-11 homolog B-like protein
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA048464

Properties

Application:	ICC, WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: LFYLTNSEYR SEQSVKLRRQ VIQVVLNGME SYQEVTVQRN CCLTLCNFSI PEELEFQYRR VNELLLSILN PTRQDESIQR IAVHLCNALV C (ATA-APrEST75336)