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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ELK-ES12220.50 | 50 µl | - | - |
Request delivery time estimate |
169.00€
|
||
ELK-ES12220.100 | 100 µl | - | - |
Request delivery time estimate |
283.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Palmitoyltransferase that catalyzes the addition of palmitate onto various... more
Product information "Anti-ZDH21"
Protein function: Palmitoyltransferase that catalyzes the addition of palmitate onto various protein substrates (PubMed:22031296). Palmitoylates sex steroid hormone receptors, including ESR1, PGR and AR, thereby regulating their targeting to the plasma membrane (PubMed:22031296). This affects rapid intracellular signaling by sex hormones via ERK and AKT kinases and the generation of cAMP, but does not affect that mediated by their nuclear receptor (PubMed:22031296). Palmitoylates FYN, regulates its localization in hair follicles and plays a key role in epidermal homeostasis and hair follicle differentiation. Through the palmitoylation of PLCB1 and the regulation of PLCB1 downstream signaling may indirectly regulate the function of the endothelial barrier and the adhesion of leukocytes to the endothelium. Has also a palmitoyltransferase activity toward ADRA1D, positively regulating its activity and expression and may thereby play a role in vascular contraction. May also palmitoylate eNOS and LCK. [The UniProt Consortium] Recommended dilutions: WB 1:500-2000. Cellular localization: Golgi apparatus membrane , Multi-pass membrane protein . Golgi apparatus, cis-Golgi network membrane , Multi-pass membrane protein . Cell membrane , Multi-pass membrane protein .
Keywords: | Anti-DHHC-21, Anti-Palmitoyltransferase ZDHHC21, Anti-Zinc finger DHHC domain-containing protein 21, Anti-DHHC domain-containing cysteine-rich protein 21, ZDH21 rabbit pAb |
Supplier: | ELK Biotechnology |
Supplier-Nr: | ES12220 |
Properties
Application: | WB |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, mouse |
Immunogen: | Synthesized peptide derived from human ZDH21 AA range: 177-227 |
Format: | Purified |
Database Information
KEGG ID : | K18932 | Matching products |
UniProt ID : | Q8IVQ6 | Matching products |
Gene ID | GeneID 340481 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
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