Anti-ZC3H8

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA034803.25	25 µl		-		7 - 10 business days*		335.00€
ATA-HPA034803.100	100 µl		-		7 - 10 business days*		446.00€

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Protein function: Acts as a transcriptional repressor of the GATA3 promoter. Sequence-specific... more

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Product information "Anti-ZC3H8"

Protein function: Acts as a transcriptional repressor of the GATA3 promoter. Sequence-specific DNA-binding factor that binds to the 5'-AGGTCTC-3' sequence within the negative cis-acting element intronic regulatory region (IRR) of the GATA3 gene. Component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III (PubMed:23932780). Induces thymocyte apoptosis when overexpressed, which may indicate a role in regulation of thymocyte homeostasis. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 67% and to rat: 63%

Keywords:	Anti-ZC3H8, Anti-ZC3HDC8, Anti-Zinc finger CCCH domain-containing protein 8
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA034803

Properties

Application:	ICC, IHC, WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: NLKAGHKNGK QKKMKRKWPG PGNKGSNALL RNSGSQEEDG KPKEKQQHLS QAFINQHT (ATA-APrEST79107)