Anti-ZBTB33

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA005732.25	25 µl		-		7 - 10 business days*		335.00€
ATA-HPA005732.100	100 µl		-		7 - 10 business days*		446.00€

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Protein function: Transcriptional regulator with bimodal DNA-binding specificity. Binds to... more

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Product information "Anti-ZBTB33"

Protein function: Transcriptional regulator with bimodal DNA-binding specificity. Binds to methylated CpG dinucleotides in the consensus sequence 5'-CGCG-3' and also binds to the non-methylated consensus sequence 5'-CTGCNA-3' also known as the consensus kaiso binding site (KBS). Recruits the N-CoR repressor complex to promote histone deacetylation and the formation of repressive chromatin structures in target gene promoters. May contribute to the repression of target genes of the Wnt signaling pathway. May also activate transcription of a subset of target genes by the recruitment of CTNND2. Represses expression of MMP7 in conjunction with transcriptional corepressors CBFA2T3, CBFA2T2 and RUNX1T1 (PubMed:23251453). [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 87% and to rat: 87%

Keywords:	Anti-KAISO, Anti-ZBTB33, Anti-Transcriptional regulator Kaiso, Anti-Zinc finger and BTB domain-containing protein 33
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA005732

Properties

Application:	ICC, IHC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: SSSPDSAVSN TSLVPQADTS QNTSFDGSLI QKMQIPTLLQ EPLSNSLKIS DIITRNTNDP GVGSKHLMEG QKIITLDTAT EIEGLSTGCK VYANIGEDTY DIVIPVKDDP DEGEARLEN (ATA-APrEST74117)