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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
600-401-FZ6 | 100 µg | - | - |
6 - 10 business days* |
684.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Anti-XAF-1 Antibody was affinity purified from monospecific antiserum by immunoaffinity... more
Product information "Anti-XAF-1"
Anti-XAF-1 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with XAF-1 from other sources has not been determined. Protein function: Plays an important role in autophagy and in particular starvation- and calcium-mediated autophagy, as well as in mitophagy. Functions upstream of the ATG12-ATG5-ATG16L1 complex and LC3, and downstream of the ULK1 and PI3-kinase complexes. Involved in xenophagy of Staphylococcus aureus. Invading S.aureus cells become entrapped in autophagosome-like WIPI1 positive vesicles targeted for lysosomal degradation. Plays also a distinct role in controlling the transcription of melanogenic enzymes and melanosome maturation, a process that is distinct from starvation- induced autophagy. May also regulate the trafficking of proteins involved in the mannose-6-phosphate receptor (MPR) recycling pathway. [The UniProt Consortium]
Keywords: | Anti-WIPI1, Anti-WIPI49, Anti-WIPI-1, Anti-WIPI 49 kDa, Anti-Atg18 protein homolog, Anti-WD repeat domain phosphoinositide-interacting protein 1, Anti-WD40 repeat protein interacting with phosphoinositides of 49 kDa |
Supplier: | Rockland Immunochemicals |
Supplier-Nr: | 600-401-FZ6 |
Properties
Application: | ELISA, IHC, IFM, WB |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, mouse |
Immunogen: | Synthetic peptide corresponding to amino acids at the C-terminus of human XAF-1. |
Format: | Purified |
Database Information
KEGG ID : | K17908 | Matching products |
UniProt ID : | Q5MNZ9 | Matching products |
Gene ID | GeneID 55062 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | -20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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