Anti-WDR77

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA027271.25	25 µl		-		7 - 10 business days*		335.00€
ATA-HPA027271.100	100 µl		-		7 - 10 business days*		446.00€

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Protein function: Non-catalytic component of the methylosome complex, composed of PRMT5, WDR77... more

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Product information "Anti-WDR77"

Protein function: Non-catalytic component of the methylosome complex, composed of PRMT5, WDR77 and CLNS1A, which modifies specific arginines to dimethylarginines in several spliceosomal Sm proteins and histones (PubMed:11756452). This modification targets Sm proteins to the survival of motor neurons (SMN) complex for assembly into small nuclear ribonucleoprotein core particles. Might play a role in transcription regulation. The methylosome complex also methylates the Piwi proteins (PIWIL1, PIWIL2 and PIWIL4), methylation of Piwi proteins being required for the interaction with Tudor domain-containing proteins and subsequent localization to the meiotic nuage (PubMed:23071334). [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 88% and to rat: 88%

Keywords:	Anti-MEP50, Anti-WDR77, Anti-MEP-50, Anti-HKMT1069, Anti-p44/Mep50, Anti-Methylosome protein 50, Anti-Androgen receptor cofactor p44, Anti-WD repeat-containing protein 77
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA027271

Properties

Application:	ICC, IHC, WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse, rat
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: SEDCSIAVLD SSLSELFRSQ AHRDFVRDAT WSPLNHSLLT TVGWDHQVVH HVVPTEPLPA PGPASVTE (ATA-APrEST76593)