Anti-WDR44

Anti-WDR44
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ELK-ES10477.50 50 µl - -

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169.00€
ELK-ES10477.100 100 µl - -

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283.00€
 
This gene encodes a protein that interacts with the small GTPase rab11. A similar protein in rat... more
Product information "Anti-WDR44"
This gene encodes a protein that interacts with the small GTPase rab11. A similar protein in rat binds the GTP-containing active form of rab11. This protein may play a role in endosome recycling. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2010], Protein function: Downstream effector for Rab11 involved in the inhibition of the intracellular ciliogenesis pathway in concert with AKT1 kinase (PubMed:31204173). When the LPAR1 receptor signaling pathway is activated, phosphorylated WDR44 binds to Rab11, thus preventing the formation of the ciliogenic Rab11-Rabin8/RAB3IP-RAB11FIP3 complex (PubMed:31204173). Together with Rab11, also participates in the regulation of vesicle recycling. [The UniProt Consortium] Recommended dilutions: WB 1:500-2000 ELISA 1:5000-20000. Cellular localization: Cytoplasm, cytosol. Cytoplasm, perinuclear region. Endosome membrane. Golgi apparatus, trans-Golgi network. Colocalized with RAB11 along microtubules oriented toward lamellipodia. .
Keywords: Anti-RPH11, Anti-Rab11BP, Anti-Rabphilin-11, Anti-Rab11-binding protein, Anti-WD repeat-containing protein 44, WDR44 rabbit pAb
Supplier: ELK Biotechnology
Supplier-Nr: ES10477

Properties

Application: WB, ELISA
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, rat, mouse
Immunogen: Synthesized peptide derived from part region of human protein
MW: 100 kD
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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