Anti-vpx

Anti-vpx
Item number Size Datasheet Manual SDS Delivery time Quantity Price
G-PACO34282.50 50 µg -

9 - 20 business days*

363.00€
 
vpx Antibody is a IgG polyclonal antibody from Assay Genie with reactivity against Simian... more
Product information "Anti-vpx"
vpx Antibody is a IgG polyclonal antibody from Assay Genie with reactivity against Simian immunodeficiency virus and for use in ELISA applications. vpx Antibody is a high quality polyclonal antibody for research use only.. Protein function: Plays a role in nuclear translocation of the viral pre- integration complex (PIC), thus is required for the virus to infect non-dividing cells. Targets specific host proteins for degradation by the 26S proteasome. Acts by associating with the cellular CUL4A-DDB1 E3 ligase complex through direct interaction with host VPRPB/DCAF-1. This change in the E3 ligase substrate specificity results in the degradation of host SAMHD1. In turn, SAMHD1 depletion allows viral replication in host myeloid cells by preventing SAMHD1-mediated hydrolysis of intracellular dNTPs necessary for reverse transcription. [The UniProt Consortium]
Keywords: Anti-vpx, Anti-Protein Vpx, Anti-X ORF protein, Anti-Viral protein X
Supplier: Assay Genie
Supplier-Nr: PACO34282

Properties

Application: ELISA
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: Simian immunodeficiency virus
Immunogen: Recombinant Simian immunodeficiency virus Protein Vpx protein (1-112AA)

Database Information

UniProt ID : P19508 | Matching products

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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