Anti-von Willebrand Factor / Factor VIII Related-Ag (Endothelial Marker) Recombinant Mouse Monoclona

Item number Size Datasheet Manual SDS Delivery time Quantity Price
ABE-12-1265-100 100 µg -

3 - 11 business days*

850.00€
 
von Willebrand Factor (vWF) is a multimeric glycoprotein that is found in endothelial cells,... more
Product information "Anti-von Willebrand Factor / Factor VIII Related-Ag (Endothelial Marker) Recombinant Mouse Monoclona"
von Willebrand Factor (vWF) is a multimeric glycoprotein that is found in endothelial cells, plasma and platelets. It acts as a carrier protein for Factor VIII and promotes platelet adhesion and aggregation. vWF undergoes a variety of posttranslational modifications that influence the affinity and availability for Factor VIII, including cleavage of the propeptide and formation of N-terminal disulfide bonds. This antibody helps to establish the endothelial nature of some lesions of disputed histogenesis, e.g. Kaposi s sarcoma and cardiac myxoma. It is widely used for differentiating vascular lesions from those of other tissue differentiation within a panel of other vascular markers althoµgh not all tumors of endothelial differentiation contain this antigen. Protein function: Important in the maintenance of hemostasis, it promotes adhesion of platelets to the sites of vascular injury by forming a molecular bridge between sub-endothelial collagen matrix and platelet-surface receptor complex GPIb-IX-V. Also acts as a chaperone for coagulation factor VIII, delivering it to the site of injury, stabilizing its heterodimeric structure and protecting it from premature clearance from plasma. [The UniProt Consortium]
Keywords: Anti-VWF, Anti-F8VWF, Anti-von Willebrand Factor / Factor VIII Related-Ag (Endothelial Marker) Recombinant Mouse Monoclonal Antibody (Clone:rVWF/1465)
Supplier: Abeomics
Supplier-Nr: 12-1265

Properties

Application: WB, IHC
Antibody Type: Monoclonal
Clone: rVWF/1465
Conjugate: No
Host: Mouse
Species reactivity: human
Immunogen: Recombinant fragment of human vWF protein (aa 1815-1939) (exact sequence is proprietary)
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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