Anti-VISTA, Rabbit Monoclonal (RM503)

Anti-VISTA, Rabbit Monoclonal (RM503)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
REV-31-1395-00-R100 100 µl - -

3 - 9 business days*

483.00€
 
Human VISTA is a 55 to 65kDa type I Ig membrane protein with the extracellular domain homologous... more
Product information "Anti-VISTA, Rabbit Monoclonal (RM503)"
Human VISTA is a 55 to 65kDa type I Ig membrane protein with the extracellular domain homologous to PD-L1. VISTA is mainly expressed on hematopoietic tissues (spleen, thymus and bone marrow) and on myeloid cells with lower expression on CD4+ and CD8+ T cells. VISTA is a new negative checkpoint regulator that potently suppresses T cell activation. Overexpression of VISTA on tumors inhibits the protective anti-tumor immunity and blockade of VISTA enhances antitumor immunity in multiple tumor models. VISTA on APC delivers negative signaling to T cells via a yet-to-identify binding partner on T cells.
Keywords: Anti-PP2135, Anti-Sisp-1, Anti-C10orf54, Anti-Platelet receptor Gi24, Anti-V-set immunoregulatory receptor, Anti-Stress-induced secreted protein-1, Anti-V-set domain-containing immunoregulatory receptor
Supplier: RevMAb Biosciences
Supplier-Nr: 31-1395-00

Properties

Application: IHC, WB
Antibody Type: Monoclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse, rat
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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