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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
REV-31-1173-00-R100 | 100 µl | - | - |
3 - 9 business days* |
483.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Recombinant Antibody. This antibody reacts to human Vimentin. It may also react to mouse or rat... more
Product information "Anti-Vimentin (human), Rabbit Monoclonal (RM289)"
Recombinant Antibody. This antibody reacts to human Vimentin. It may also react to mouse or rat Vimentin, as predicted by immunogen homology. Applications: WB, IHC. Source: Rabbit. Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide. Vimentin is a developmentally regulated intermediate filament protein (IFP) found in mesenchymal cells. It is believed to be involved in the intracellular transport of proteins between the nucleus and plasma membrane. Unlike other IFP proteins, vimentin is expressed, along with desmin, during the early stages of cellular development. During the development process, vimentin is exchanged for new, tissue-specific IFPs. Vimentin has been implicated to be involved in the rate of steroid synthesis via its role as a storage network for steroidogenic cholesterol containing lipid droplets. Vimentin phosphorylation by a protein kinase causes the breakdown of intermediate filaments and activation of an ATP and myosin light chain dependent contractile event. This results in cytoskeletal changes that facilitate the interaction of the lipid droplets within mitochondria and subsequent transport of cholesterol to the organelles lead to an increase in steroid synthesis. Vimentin has been used as a sarcoma tumor marker to identify mesenchyme.
Supplier: | RevMAb Biosciences |
Supplier-Nr: | 31-1173-00 |
Properties
Application: | WB, IHC |
Antibody Type: | Monoclonal |
Clone: | RM289 |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human |
Format: | Purified |
Database Information
KEGG ID : | K07606 | Matching products |
UniProt ID : | P08670 | Matching products |
Gene ID | GeneID 7431 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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