Anti-VEGF (Bevacizumab Biosimilar In Vivo Antibody)

Item number	Size	Manual	SDS	Delivery time	Price
G-IVMB0232.1	1 mg	-	-	9 - 20 business days*	266.00€
G-IVMB0232.5	5 mg	-	-	9 - 20 business days*	919.00€
G-IVMB0232.25	25 mg	-	-	9 - 20 business days*	3,487.00€
G-IVMB0232.50	50 mg	-	-	9 - 20 business days*	5,338.00€
G-IVMB0232.100	100 mg	-	-	9 - 20 business days*	7,254.00€

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Endotoxin level: < 1.0 EU/mg as determined by the LAL method. Protein function: Growth factor... more

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Product information "Anti-VEGF (Bevacizumab Biosimilar In Vivo Antibody)"

Endotoxin level: < 1.0 EU/mg as determined by the LAL method. Protein function: Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. NRP1/Neuropilin-1 binds isoforms VEGF-165 and VEGF-145. Isoform VEGF165B binds to KDR but does not activate downstream signaling pathways, does not activate angiogenesis and inhibits tumor growth. Binding to NRP1 receptor initiates a signaling pathway needed for motor neuron axon guidance and cell body migration, including for the caudal migration of facial motor neurons from rhombomere 4 to rhombomere 6 during embryonic development. Also binds the DEAR/FBXW7-AS1 receptor (PubMed:17446437). [The UniProt Consortium]

Keywords:	Anti-VPF, Anti-VEGF, Anti-VEGFA, Anti-VEGF-A, Anti-Vascular permeability factor, Anti-Vascular endothelial growth factor A
Supplier:	Assay Genie
Supplier-Nr:	IVMB0232

Properties

Application:	WB, ELISA, FC, IP, Neutr., WB
Antibody Type:	Monoclonal
Clone:	A4.6.1
Conjugate:	No
Host:	Human
Species reactivity:	human
Purity:	>95% monomer (analytical SEC)
Format:	Functional Grade