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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| G-IVMB0234.500 | 500 µg | - | - |
9 - 20 business days* |
620.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Endotoxin level: < 1.0 EU/mg as determined by the LAL method. Protein function: Growth factor... more
Product information "Anti-VEGF (Bevacizumab Biosimilar In Vivo Antibody (Fc Reduced))"
Endotoxin level: < 1.0 EU/mg as determined by the LAL method. Protein function: Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. NRP1/Neuropilin-1 binds isoforms VEGF-165 and VEGF-145. Isoform VEGF165B binds to KDR but does not activate downstream signaling pathways, does not activate angiogenesis and inhibits tumor growth. Binding to NRP1 receptor initiates a signaling pathway needed for motor neuron axon guidance and cell body migration, including for the caudal migration of facial motor neurons from rhombomere 4 to rhombomere 6 during embryonic development. Also binds the DEAR/FBXW7-AS1 receptor (PubMed:17446437). [The UniProt Consortium]
| Keywords: | Anti-VPF, Anti-VEGF, Anti-VEGFA, Anti-VEGF-A, Anti-Vascular permeability factor, Anti-Vascular endothelial growth factor A |
| Supplier: | Assay Genie |
| Supplier-Nr: | IVMB0234 |
Properties
| Application: | WB, ELISA, FC, IP, Neutr., WB |
| Antibody Type: | Monoclonal |
| Clone: | A4.6.1 |
| Conjugate: | No |
| Host: | Human |
| Species reactivity: | human |
| Purity: | >95% monomer (analytical SEC) |
| Format: | Functional Grade |
Database Information
| KEGG ID : | K05448 | Matching products |
| UniProt ID : | P15692 | Matching products |
| Gene ID | GeneID 7422 | Matching products |
Handling & Safety
| Storage: | +4°C |
| Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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