Anti-VDAC

Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-F49742-0.08ML 80 µl - -

3 - 10 business days*

326.00€
NSJ-F49742-0.4ML 400 µl - -

3 - 10 business days*

702.00€
 
In 1X PBS, pH 7.4, with 0.09% sodium azide. VDAC1 forms a channel through the mitochondrial outer... more
Product information "Anti-VDAC"
In 1X PBS, pH 7.4, with 0.09% sodium azide. VDAC1 forms a channel through the mitochondrial outer membrane and also the plasma membrane. The channel at the outer mitochondrial membrane allows diffusion of small hydrophilic molecules, in the plasma membrane it is involved in cell volume regulation and apoptosis. It adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation-selective. The protein may participate in the formation of the permeability transition pore complex (PTPC) responsible for the release of mitochondrial products that triggers apoptosis. Protein function: Forms a channel through the mitochondrial outer membrane and also the plasma membrane. The channel at the outer mitochondrial membrane allows diffusion of small hydrophilic molecules, in the plasma membrane it is involved in cell volume regulation and apoptosis. It adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation-selective (PubMed:11845315, PubMed:18755977, PubMed:20230784, PubMed:8420959). May participate in the formation of the permeability transition pore complex (PTPC) responsible for the release of mitochondrial products that triggers apoptosis (PubMed:15033708, PubMed:25296756). [The UniProt Consortium]
Keywords: Anti-VDAC, Anti-VDAC1, Anti-VDAC-1, Anti-hVDAC1, Anti-Porin 31HL, Anti-Porin 31HM, Anti-Plasmalemmal porin, Anti-Outer mitochondrial membrane protein porin 1, Anti-Voltage-dependent anion-selective channel protein 1, VDAC Antibody
Supplier: NSJ Bioreagents
Supplier-Nr: F49742

Properties

Application: WB, IHC, FC, ELISA
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse
Immunogen: A portion of amino acids 1-30 from human VDAC1 was used as the immunogen for this VDAC antibody.
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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