Anti-VCPIP1

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA023932.25	25 µl		-		7 - 10 business days*		335.00€
ATA-HPA023932.100	100 µl		-		7 - 10 business days*		446.00€

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Protein function: Deubiquitinating enzyme involved in DNA repair and reassembly of the Golgi... more

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Product information "Anti-VCPIP1"

Protein function: Deubiquitinating enzyme involved in DNA repair and reassembly of the Golgi apparatus and the endoplasmic reticulum following mitosis (PubMed:32649882). Necessary for VCP-mediated reassembly of Golgi stacks after mitosis. Plays a role in VCP-mediated formation of transitional endoplasmic reticulum (tER). Mediates dissociation of the ternary complex containing STX5A, NSFL1C and VCP. Also involved in DNA repair following phosphorylation by ATM or ATR: acts by catalyzing deubiquitination of SPRTN, thereby promoting SPRTN recruitment to chromatin and subsequent proteolytic cleavage of covalent DNA-protein cross-links (DPCs) (PubMed:32649882). Hydrolyzes 'Lys-11'- and 'Lys-48'-linked polyubiquitin chains (PubMed:23827681). [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 92% and to rat: 95%

Keywords:	Anti-Deubiquitinating protein VCPIP1, Anti-VCP/p47 complex-interacting 135-kDa protein, Anti-Valosin-containing protein p97/p47 complex-interacting protein 1, Anti-Valosin-containing protein p97/p47 complex-interacting protein p135
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA023932

Properties

Application:	IHC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: LLCGALSELH VPPEWLAPGG KLYNLAKSTH GQLRTDKNYS FPLNNLVCSY DSVKDVLVPD YGMSNLTACN WCHGTSVRKV RGDGSIVYLD G (ATA-APrEST76385)