Anti-VAMP8

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
A304-350A-T	10 µl (10 µg)		-		2 - 8 business days*		164.00€
A304-350A	100 µl (100 µg)		-		2 - 8 business days*		588.00€

If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk

Protein function: SNAREs, soluble N-ethylmaleimide-sensitive factor- attachment protein... more

Close menu

Product information "Anti-VAMP8"

Protein function: SNAREs, soluble N-ethylmaleimide-sensitive factor- attachment protein receptors, are essential proteins for fusion of cellular membranes. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion. VAMP8 is a SNARE involved in autophagy through the direct control of autophagosome membrane fusion with the lysososome membrane via its interaction with the STX17-SNAP29 binary t-SNARE complex (PubMed:23217709, PubMed:25686604). Also required for dense-granule secretion in platelets (PubMed:12130530). Plays also a role in regulated enzyme secretion in pancreatic acinar cells. Involved in the abscission of the midbody during cell division, which leads to completely separate daughter cells. Involved in the homotypic fusion of early and late endosomes. [The UniProt Consortium]

Keywords:	Anti-EDB, Anti-VAMP-8, Anti-Endobrevin, Anti-Vesicle-associated membrane protein 8
Supplier:	Bethyl Laboratories
Supplier-Nr:	A304-350A

Properties

Application:	WB, IP
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human (Expected: orangutan)
Immunogen:	synthetic peptide. The epitope recognized by A304-350A-T maps to a region between residue 1 to 50 of human Vesicle-Associated Membrane Protein 8 using the numbering given in entry NP_003752.2 (GeneID 8673).
Format:	Antigen Affinity Purified