Anti-VAMP8

Anti-VAMP8
Item number Size Datasheet Manual SDS Delivery time Quantity Price
A304-350A-T 20 µl (2 blots) -

3 - 9 business days*

131.00€
A304-350A-M 100 µl (10 blots) -

3 - 9 business days*

313.00€
A304-350A 100 µl (100 µg) -

3 - 9 business days*

465.00€
 
Protein function: SNAREs, soluble N-ethylmaleimide-sensitive factor- attachment protein... more
Product information "Anti-VAMP8"
Protein function: SNAREs, soluble N-ethylmaleimide-sensitive factor- attachment protein receptors, are essential proteins for fusion of cellular membranes. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion. VAMP8 is a SNARE involved in autophagy through the direct control of autophagosome membrane fusion with the lysososome membrane via its interaction with the STX17-SNAP29 binary t-SNARE complex (PubMed:23217709, PubMed:25686604). Also required for dense-granule secretion in platelets (PubMed:12130530). Plays also a role in regulated enzyme secretion in pancreatic acinar cells. Involved in the abscission of the midbody during cell division, which leads to completely separate daughter cells. Involved in the homotypic fusion of early and late endosomes. [The UniProt Consortium]
Keywords: Anti-EDB, Anti-VAMP-8, Anti-Endobrevin, Anti-Vesicle-associated membrane protein 8
Supplier: Bethyl Laboratories
Supplier-Nr: A304-350A

Properties

Application: WB, IP
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human (Expected: Orangutan)
Immunogen: synthetic peptide. The epitope recognized by A304-350A-T maps to a region between residue 1 to 50 of human Vesicle-Associated Membrane Protein 8 using the numbering given in entry NP_003752.2 (GeneID 8673).
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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