Anti-USP5

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA006756.25	25 µl		-		7 - 10 business days*		335.00€
ATA-HPA006756.100	100 µl		-		7 - 10 business days*		446.00€

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Protein function: Cleaves linear and branched multiubiquitin polymers with a marked preference... more

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Product information "Anti-USP5"

Protein function: Cleaves linear and branched multiubiquitin polymers with a marked preference for branched polymers. Involved in unanchored 'Lys- 48'-linked polyubiquitin disassembly. Binds linear and 'Lys-63'-linked polyubiquitin with a lower affinity. Knock-down of USP5 causes the accumulation of p53/TP53 and an increase in p53/TP53 transcriptional activity because the unanchored polyubiquitin that accumulates is able to compete with ubiquitinated p53/TP53 but not with MDM2 for proteasomal recognition. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 97% and to rat: 97%

Keywords:	Anti-USP5, Anti-ISOT, EC=3.4.19.12, Anti-Isopeptidase T, Anti-Ubiquitin thioesterase 5, Anti-Deubiquitinating enzyme 5, Anti-Ubiquitin carboxyl-terminal hydrolase 5, Anti-Ubiquitin-specific-processing protease 5
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA006756

Properties

Application:	ICC, IHC, WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse, rat
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: YVDKLEKIFQ NAPTDPTQDF STQVAKLGHG LLSGEYSKPV PESGDGERVP EQKEVQDGIA PRMFKALIGK GHPEFSTNRQ QDAQEFFLHL INMVERNCRS SENPNEVF (ATA-APrEST70800)