Anti-USP37

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA045160.25	25 µl		-		7 - 10 business days*		335.00€
ATA-HPA045160.100	100 µl		-		7 - 10 business days*		446.00€

If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk

Protein function: Deubiquitinase that antagonizes the anaphase-promoting complex (APC/C) during... more

Close menu

Product information "Anti-USP37"

Protein function: Deubiquitinase that antagonizes the anaphase-promoting complex (APC/C) during G1/S transition by mediating deubiquitination of cyclin-A (CCNA1 and CCNA2), thereby promoting S phase entry. Specifically mediates deubiquitination of 'Lys-11'-linked polyubiquitin chains, a specific ubiquitin-linkage type mediated by the APC/C complex. Also mediates deubiquitination of 'Lys-48'-linked polyubiquitin chains in vitro. Phosphorylation at Ser-628 during G1/S phase maximizes the deubiquitinase activity, leading to prevent degradation of cyclin-A (CCNA1 and CCNA2) (PubMed:21596315). Plays an important role in the regulation of DNA replication by stabilizing the licensing factor CDT1 (PubMed:27296872). [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 92% and to rat: 92%

Keywords:	Anti-USP37, Anti-KIAA1594, Anti-Ubiquitin thioesterase 37, Anti-Deubiquitinating enzyme 37, Anti-Ubiquitin carboxyl-terminal hydrolase 37, Anti-Ubiquitin-specific-processing protease 37
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA045160

Properties

Application:	ICC, IHC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: TGITKWKEGS FEIVEKENKV SLVVHYNTGG IPRIFQLSHN IKNVVLRPSG AKQSRLMLTL QDNSFLSIDK VPSKDAEEMR LFLDAVHQNR LPAAMKPSQG SGSFGAILGS RTSQKETSR (ATA-APrEST70814)