Anti-URM1

Anti-URM1
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ARG40060.100 100 µl - -

6 - 14 business days*

624.00€
 
Protein function: Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA... more
Product information "Anti-URM1"
Protein function: Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2- thiolation reaction by being thiocarboxylated (-COSH) at its C- terminus by MOCS3. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins such as MOCS3, ATPBD3, CTU2, USP15 and CAS. The thiocarboxylated form serves as substrate for conjugation and oxidative stress specifically induces the formation of UBL-protein conjugates. [The UniProt Consortium]
Keywords: Anti-C9orf74, Anti-Ubiquitin-related modifier 1
Supplier: Arigo Biolaboratories
Supplier-Nr: ARG40060

Properties

Application: WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: rat
Immunogen: Recombinant fusion protein corresponding to aa. 1-63 of Human URM1 (NP_001252511.1)
MW: 11.4 kD
Format: Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: °C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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