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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
600-401-FU2 | 100 µg | - | - |
6 - 10 business days* |
684.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Anti-UHRF1BP1L Antibody was affinity purified from monospecific antiserum by immunoaffinity... more
Product information "Anti-UHRF1BP1L"
Anti-UHRF1BP1L Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. At least two isoforms of UHRF1BP1L are known to exist, this antibody will recognize both isoforms. UHRF1BP1L antibody is predicted to not cross-react with UHRF1BP1 Protein function: The UBE2V1-UBE2N and UBE2V2-UBE2N heterodimers catalyze the synthesis of non-canonical 'Lys-63'-linked polyubiquitin chains. This type of polyubiquitination does not lead to protein degradation by the proteasome. Mediates transcriptional activation of target genes. Plays a role in the control of progress through the cell cycle and differentiation. Plays a role in the error-free DNA repair pathway and contributes to the survival of cells after DNA damage. Acts together with the E3 ligases, HLTF and SHPRH, in the 'Lys-63'-linked poly-ubiquitination of PCNA upon genotoxic stress, which is required for DNA repair. Appears to act together with E3 ligase RNF5 in the 'Lys-63'-linked polyubiquitination of JKAMP thereby regulating JKAMP function by decreasing its association with components of the proteasome and ERAD. Promotes TRIM5 capsid-specific restriction activity and the UBE2V1-UBE2N heterodimer acts in concert with TRIM5 to generate 'Lys-63'-linked polyubiquitin chains which activate the MAP3K7/TAK1 complex which in turn results in the induction and expression of NF-kappa-B and MAPK-responsive inflammatory genes. [The UniProt Consortium]
Keywords: | Anti-BLU, Anti-UBE2N, Anti-Ubc13, Anti-UbcH13, EC=6.3.2.19, Anti-Ubiquitin-protein ligase N, Anti-Ubiquitin carrier protein N, Anti-Ubiquitin-conjugating enzyme E2 N, Anti-Bendless-like ubiquitin-conjugating enzyme |
Supplier: | Rockland Immunochemicals |
Supplier-Nr: | 600-401-FU2 |
Properties
Application: | ELISA, IHC, IFM, WB |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, mouse |
Immunogen: | 17 amino acid synthetic peptide near the internal region of human UHRF1BP1L. |
Format: | Purified |
Database Information
KEGG ID : | K10580 | Matching products |
UniProt ID : | P61088 | Matching products |
Gene ID | GeneID 7334 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | -20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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