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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ABE-36-2030-20 | 20 µg | - | - |
3 - 11 business days* |
375.00€
|
||
ABE-36-2030-100 | 100 µg | - | - |
3 - 11 business days* |
853.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
This gene encodes a class III member of the beta tubulin protein family. Beta tubulins are one of... more
Product information "Anti-Tubulin beta 3 / TUBB3 (Neuronal & Stem Cell Marker) Monoclona Antibody (Clone: TUBB3/3732)"
This gene encodes a class III member of the beta tubulin protein family. Beta tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. This protein is primarily expressed in neurons and may be involved in neurogenesis and axon guidance and maintenance. Mutations in this gene are the cause of congenital fibrosis of the extraocular muscles type 3.In adults, tubulin beta 3 (TUBB3) is primarily expressed in neurons and is commonly used as a neuronal marker. It plays an important role in neuronal cell proliferation and differentiation. Protein function: Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. TUBB3 plays a critical role in proper axon guidance and mantainance. Binding of NTN1/Netrin-1 to its receptor UNC5C might cause dissociation of UNC5C from polymerized TUBB3 in microtubules and thereby lead to increased microtubule dynamics and axon repulsion (PubMed:28483977). Plays a role in dorsal root ganglion axon projection towards the spinal cord (PubMed:28483977). [The UniProt Consortium]
Keywords: | Anti-TUBB3, Anti-TUBB4, Anti-Tubulin beta-III, Anti-Tubulin beta-3 chain, Anti-Tubulin beta-4 chain, Anti-Tubulin beta 3 / TUBB3 (Neuronal & Stem Cell Marker) Monoclona Antibody (Clone: TUBB3/3732) |
Supplier: | Abeomics |
Supplier-Nr: | 36-2030 |
Properties
Application: | IHC |
Antibody Type: | Monoclonal |
Clone: | TUBB3/3732 |
Conjugate: | No |
Host: | Mouse |
Species reactivity: | human |
Immunogen: | A synthetic peptide (aa 437-450) of human Tubulin beta 3 protein (TUBB3), coupled to KLH. |
Database Information
KEGG ID : | K07375 | Matching products |
UniProt ID : | Q13509 | Matching products |
Gene ID | GeneID 10381 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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You will get a certificate here
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