Anti-Troponin C (cardiac)

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
NSJ-R30872	100 µg		-	-	3 - 10 business days*		755.00€

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0.5mg/ml if reconstituted with 0.2ml sterile DI water. Troponin C, also called TNNC1, and TNC, is... more

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Product information "Anti-Troponin C (cardiac)"

0.5mg/ml if reconstituted with 0.2ml sterile DI water. Troponin C, also called TNNC1, and TNC, is a protein that in humans is encoded by the TNNC1 gene. Using a monochromosomal hybrid panel, the TNNC1 gene is mapped to chromosome 3, subsequent analysis of the Genebridge 4 radiation hybrid panel localized the gene to 3p in a region consistent with the earlier assignment. Circular dichroism measurements revealed changes in the secondary structures of the TNNC1 mutants A8V, C84Y, and D145E. Protein function: Troponin is the central regulatory protein of striated muscle contraction. Tn consists of three components: Tn-I which is the inhibitor of actomyosin ATPase, Tn-T which contains the binding site for tropomyosin and Tn-C. The binding of calcium to Tn-C abolishes the inhibitory action of Tn on actin filaments. [The UniProt Consortium]

Keywords:	Anti-TNNC, Anti-TN-C, Anti-TNNC1, Anti-Troponin C, slow skeletal and cardiac muscles, Troponin C Antibody (cardiac)
Supplier:	NSJ Bioreagents
Supplier-Nr:	R30872

Properties

Application:	WB, IHC (paraffin)
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse, rat
Immunogen:	Amino acid sequence from the N-terminus of human cardiac Troponin C (MDDIYKAAVEQLTEEQKN)
Format:	Purified