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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ABE-11-8031-25 | 25 µg | - |
3 - 11 business days* |
134.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
TRK Fused gene (TFG) encodes a protein that plays a role in the normal dynamic function of the... more
Product information "Anti-TRK Fused gene"
TRK Fused gene (TFG) encodes a protein that plays a role in the normal dynamic function of the endoplasmic reticulum (ER) and its associated microtubules. It is a conserved regulator of protein secretion that assembles into an oligomeric matrix at the interface between the ER and ER Golgi intermediate compartments in metazoans cells. Originally TFG was identified as a fusion partner of the NTRK1 gene in human papillary thyroid carcinoma. It is also involved in another chromosome translocation with the ALK gene in anaplastic large-cell lymphomas. It is located on the q arm of human chromosome 3 and encodes a ubiquitously expressed cytoplasmic protein. Structural analysis reveals TFG containing a coiled-coil (CC) domain and a serine, proline, tyrosine, glycine and glutamine (SPYGQ)-rich region. Interestingly, the TFG protein interacts with the NF-kappaB essential modulator and TRAF family member-associated NF-kappaB activator proteins, suggesting that it may play a key role in NF-kappaB regulation. Protein function: Plays a role in the normal dynamic function of the endoplasmic reticulum (ER) and its associated microtubules (PubMed:23479643, PubMed:27813252). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus (PubMed:21478858). [The UniProt Consortium]
Keywords: | Anti-TFG, Anti-Protein TFG, Anti-TRK-fused gene protein, Polyclonal Antibody to TRK Fused gene |
Supplier: | Abeomics |
Supplier-Nr: | 11-8031-25 |
Properties
Application: | IHC, WB |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human (Expected: mouse) |
Immunogen: | A partial length recombinant TRK Fused gene protein (amino acids 196-400) was used as the immunogen for this antibody. |
Format: | Purified |
Database Information
KEGG ID : | K09292 | Matching products |
UniProt ID : | Q92734 | Matching products |
Gene ID | GeneID 10342 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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