Anti-TRIP10/CIP4

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
A301-186A-T	10 µl (2 µg)		-		2 - 8 business days*		164.00€
A301-186A	100 µl		-		2 - 8 business days*		588.00€

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Protein function: Required for translocation of GLUT4 to the plasma membrane in response to... more

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Product information "Anti-TRIP10/CIP4"

Protein function: Required for translocation of GLUT4 to the plasma membrane in response to insulin signaling. Required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during endocytosis. Binds to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promotes membrane invagination and the formation of tubules. Also promotes CDC42-induced actin polymerization by recruiting WASL/N- WASP which in turn activates the Arp2/3 complex. Actin polymerization may promote the fission of membrane tubules to form endocytic vesicles. Required for the formation of podosomes, actin-rich adhesion structures specific to monocyte-derived cells. May be required for the lysosomal retention of FASLG/FASL. [The UniProt Consortium]

Keywords:	Anti-hSTP, Anti-CIP4, Anti-TRIP10, Anti-TRIP-10, Anti-Protein Felic, Anti-Salt tolerant protein, Anti-TR-interacting protein 10, Anti-Cdc42-interacting protein 4, Anti-Thyroid receptor-interacting protein 10
Supplier:	Bethyl Laboratories
Supplier-Nr:	A301-186A

Properties

Application:	WB, IP
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse (Expected: rat, orangutan)
Immunogen:	synthetic peptide. The epitope recognized by A301-186A-T maps to a region between residue 551 and 601 of human thyroid receptor interacting protein 10 (Cdc42-interacting protein 4) using the numbering given in entry AAM46851.1 (GeneID 9322).
Format:	Antigen Affinity Purified