Anti-Trim29

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ABE-11-7535-25	25 µg		-		3 - 11 business days*		134.00€

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Protein function: Plays a crucial role in the regulation of macrophage activation in response to... more

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Product information "Anti-Trim29"

Protein function: Plays a crucial role in the regulation of macrophage activation in response to viral or bacterial infections within the respiratory tract. Mechanistically, TRIM29 interacts with IKBKG/NEMO in the lysosome where it induces its 'Lys-48' ubiquitination and subsequent degradation. In turn, the expression of type I interferons and the production of proinflammatory cytokines are inhibited. Additionally, induces the 'Lys-48' ubiquitination of TMEM173/STING in a similar way, leading to its degradation. [The UniProt Consortium]

Keywords:	Anti-ATDC, Anti-TRIM29, Anti-Tripartite motif-containing protein 29, Anti-Ataxia telangiectasia group D-associated protein, Polyclonal Antibody to Trim29
Supplier:	Abeomics
Supplier-Nr:	11-7535-25

Properties

Application:	IHC, WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	A partial length recombinant Trim29 protein (amino acids 1-206) was used as the immunogen for this antibody.
Format:	Purified