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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
NSJ-F48183-0.08ML | 80 µl | - | - |
3 - 10 business days* |
326.00€
|
||
NSJ-F48183-0.4ML | 400 µl | - | - |
3 - 10 business days* |
702.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
In 1X PBS, pH 7.4, with 0.09% sodium azide. TERF1/TRF1 is a telomere specific protein which is a... more
Product information "Anti-TRF1"
In 1X PBS, pH 7.4, with 0.09% sodium azide. TERF1/TRF1 is a telomere specific protein which is a component of the telomere nucleoprotein complex. This protein is present at telomeres throughout the cell cycle and functions as an inhibitor of telomerase, acting in cis to limit the elongation of individual chromosome ends. The protein structure contains a C-terminal Myb motif, a dimerization domain near its N-terminus and an acidic N-terminus. Protein function: Binds the telomeric double-stranded 5'-TTAGGG-3' repeat and negatively regulates telomere length. Involved in the regulation of the mitotic spindle. Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double- stranded 5'-TTAGGG-3' repeats added by telomerase and protects chromosome ends, without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways. [The UniProt Consortium]
Keywords: | Anti-PIN2, Anti-TERF1, Anti-NIMA-interacting protein 2, Anti-Telomeric protein Pin2/TRF1, Anti-TTAGGG repeat-binding factor 1, Anti-Telomeric repeat-binding factor 1, TRF1 Antibody |
Supplier: | NSJ Bioreagents |
Supplier-Nr: | F48183 |
Properties
Application: | WB, ELISA |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human |
Immunogen: | A portion of amino acids 337-366 from the human protein was used as the immunogen for this TRF1 antibody. |
Format: | Purified |
Database Information
KEGG ID : | K11110 | Matching products |
UniProt ID : | P54274 | Matching products |
Gene ID | GeneID 7013 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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