Anti-TRF1

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG41071.100	100 µl		-	-	6 - 14 business days*		624.00€

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Protein function: Binds the telomeric double-stranded 5'-TTAGGG-3' repeat and negatively... more

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Product information "Anti-TRF1"

Protein function: Binds the telomeric double-stranded 5'-TTAGGG-3' repeat and negatively regulates telomere length. Involved in the regulation of the mitotic spindle. Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double- stranded 5'-TTAGGG-3' repeats added by telomerase and protects chromosome ends, without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways. [The UniProt Consortium]

Keywords:	Anti-PIN2, Anti-TERF1, Anti-NIMA-interacting protein 2, Anti-Telomeric protein Pin2/TRF1, Anti-TTAGGG repeat-binding factor 1, Anti-Telomeric repeat-binding factor 1
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG41071

Properties

Application:	WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse
Immunogen:	Synthetic peptide derived from Human TRF1
MW:	50 kD
Format:	Affinity Purified