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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
T8180-04C.100 | 100 µg | - | - |
3 - 19 business days* |
688.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Apoptosis, or programmed cell death, occurs during normal cellular differentiation and... more
Product information "Anti-TRAIL (TNF-Related Apoptosis Inducing Ligand, Apo2L, TL2, TNFSF10), clone 4H289"
Apoptosis, or programmed cell death, occurs during normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by certain cytokines including TNF and Fas ligand in the TNF family through their death domain containing receptors, TNFR1 and Fas. A novel member in the TNF family was recently identified and designated TRAIL (for TNF-related apoptosis-inducing ligand) and Apo-2L (for Apo-2 ligand) (1,2). TRAIL is a type II membrane protein and expressed in a variety of human tissues. Two novel death domain containing receptors DR4 and DR5 have been identified as the receptor for TRAIL3-6. Like TNF and Fas ligand, TRAIL induces apoptosis and NF-kB activation in many tissues and cells. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 1-2ug/ml, Whole cell lysate from Jurkat cells can be used as positive control and a 32kD band, which represents a membrane bound form of TRAIL, is detected. , Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Freeze at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Keywords: | Anti-CD253, Anti-APO2L, Anti-Apo-2L, Anti-TNFSF10, Anti-Apo-2 ligand, Anti-Protein TRAIL, Anti-TNF-related apoptosis-inducing ligand, Anti-Tumor necrosis factor ligand superfamily member 10 |
Supplier: | United States Biological |
Supplier-Nr: | T8180-04C |
Properties
Application: | WB |
Antibody Type: | Monoclonal |
Clone: | 4H289 |
Conjugate: | No |
Host: | Mouse |
Species reactivity: | human |
Format: | Purified |
Database Information
KEGG ID : | K04721 | Matching products |
UniProt ID : | P50591 | Matching products |
Gene ID | GeneID 8743 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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