Anti-TRAF2

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
600-401-B27S	25 µl		-	-	6 - 10 business days*		180.00€
600-401-B27	100 µg		-	-	6 - 10 business days*		684.00€

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Protein function: Regulates activation of NF-kappa-B and JNK and plays a central role in the... more

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Product information "Anti-TRAF2"

Protein function: Regulates activation of NF-kappa-B and JNK and plays a central role in the regulation of cell survival and apoptosis. Required for normal antibody isotype switching from IgM to IgG. Has E3 ubiquitin-protein ligase activity and promotes 'Lys-63'- linked ubiquitination of target proteins, such as BIRC3, RIPK1 and TICAM1. Is an essential constituent of several E3 ubiquitin- protein ligase complexes, where it promotes the ubiquitination of target proteins by bringing them into contact with other E3 ubiquitin ligases. Regulates BIRC2 and BIRC3 protein levels by inhibiting their autoubiquitination and subsequent degradation, this does not depend on the TRAF2 RING-type zinc finger domain. [The UniProt Consortium]

Keywords:	Anti-TRAF2, Anti-TRAP3, EC=6.3.2.-, Anti-TNF receptor-associated factor 2, Anti-E3 ubiquitin-protein ligase TRAF2, Anti-Tumor necrosis factor type 2 receptor-associated protein 3
Supplier:	Rockland Immunochemicals
Supplier-Nr:	600-401-B27

Properties

Application:	ELISA, IFM, WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human (Expected: mouse)
Immunogen:	synthetic peptide coresponding to an internal region of human TRAF2 protein
Format:	Affinity Purified