Anti-TRADD

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG53680.500	500 µl		-	-	6 - 14 business days*		608.00€

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Protein function: The nuclear form acts as a tumor suppressor by preventing ubiquitination and... more

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Product information "Anti-TRADD"

Protein function: The nuclear form acts as a tumor suppressor by preventing ubiquitination and degradation of isoform p19ARF/ARF of CDKN2A by TRIP12: acts by interacting with TRIP12, leading to disrupt interaction between TRIP12 and isoform p19ARF/ARF of CDKN2A. Adapter molecule for TNFRSF1A/TNFR1 that specifically associates with the cytoplasmic domain of activated TNFRSF1A/TNFR1 mediating its interaction with FADD. Overexpression of TRADD leads to two major TNF-induced responses, apoptosis and activation of NF-kappa-B. [The UniProt Consortium]

Keywords:	Anti-TRADD, Anti-TNFRSF1A-associated via death domain, Anti-TNFR1-associated DEATH domain protein, Anti-Tumor necrosis factor receptor type 1-associated DEATH domain protein
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG53680

Properties

Application:	IHC (paraffin)
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Synthetic peptide derived from C-terminus of human TRADD
Format:	Liquid