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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ELK-ES12602.50 | 50 µl | - | - |
Request delivery time estimate |
169.00€
|
||
ELK-ES12602.100 | 100 µl | - | - |
Request delivery time estimate |
283.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
This gene encodes a member of the tropomyosin family of actin-binding proteins involved in the... more
Product information "Anti-TPM4"
This gene encodes a member of the tropomyosin family of actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosins are dimers of coiled-coil proteins that polymerize end-to-end along the major groove in most actin filaments. They provide stability to the filaments and regulate access of other actin-binding proteins. In muscle cells, they regulate muscle contraction by controlling the binding of myosin heads to the actin filament. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2009], Protein function: Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments. Binds calcium (PubMed:1836432). [The UniProt Consortium] Recommended dilutions: WB 1:500-2000. Cellular localization: Cytoplasm, cytoskeleton . Associates with F-actin stress fibers. .
Keywords: | Anti-TPM4, Anti-TM30p1, Anti-Tropomyosin-4, Anti-Tropomyosin alpha-4 chain, TPM4 rabbit pAb |
Supplier: | ELK Biotechnology |
Supplier-Nr: | ES12602 |
Properties
Application: | WB |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
Immunogen: | Synthesized peptide derived from human TPM4 AA range: 127-177 |
Format: | Purified |
Database Information
KEGG ID : | K10375 | Matching products |
UniProt ID : | P67936 | Matching products |
Gene ID | GeneID 7171 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
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