Anti-Toso

Anti-Toso
Item number Size Datasheet Manual SDS Delivery time Quantity Price
600-401-FM2 100 µg - -

6 - 10 business days*

684.00€
 
Anti-Toso Antibody was affinity purified from monospecific antiserum by immunoaffinity... more
Product information "Anti-Toso"
Anti-Toso Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with Toso from other sources has not been determined. Protein function: Component of the signaling pathway of IL-1 and Toll-like receptors. Inhibits cell activation by microbial products. Recruits IRAK1 to the IL-1 receptor complex. Inhibits IRAK1 phosphorylation and kinase activity (PubMed:11751856). Connects the ubiquitin pathway to autophagy by functioning as a ubiquitin- ATG8 family adapter and thus mediating autophagic clearance of ubiquitin conjugates. The TOLLIP-dependent selective autophagy pathway plays an important role in clearance of cytotoxic polyQ proteins aggregates (PubMed:25042851). [The UniProt Consortium]
Keywords: Anti-TOLLIP, Anti-Toll-interacting protein
Supplier: Rockland Immunochemicals
Supplier-Nr: 600-401-FM2

Properties

Application: ELISA, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human
Immunogen: 13 amino acid synthetic peptide from near the C-terminus of human Toso.
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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