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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
BOT-BNUM0488-50 | 50 µl | - |
Request delivery time estimate |
565.00€
|
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
DNA topoisomerases are nuclear enzymes that regulate the topological structure of DNA in... more
Product information "Anti-Topoisomerase I, MT(TOP1MT/488), 1mg/mL"
DNA topoisomerases are nuclear enzymes that regulate the topological structure of DNA in eukaryotic cells by transiently breaking and rejoining DNA strands. Due to their roles in DNA replication, recombination, and transcription, DNA topoisomerases have been identified as targets of numerous anticancer drugs. Mitochondrial Topo I (DNA topoisomerase I, mitochondrial) is a 601 amino acid protein that primarily acts to relieve DNA strain that may occur during duplication of mitochondrial DNA. As a type IB topoisomerase, mitochondrial Topo I requires a divalent metal, either, calcium or magnesium, as well as an alkaline pH for optimal activity. Primary antibodies are available purified, or with a selection of fluorescent CF(R) Dyes and other labels. CF(R) Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF(R)405S and CF(R)405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors. Concentration: 1 mg/mL Storage buffer: PBS, no BSA, no azide
Keywords: | Topoisomerase I, MT(TOP1MT/488), 1mg/mL, |
Supplier: | Biotium |
Supplier-Nr: | BNUM0488 |
Properties
Application: | FC, intracellular (verif.), IF (verif.), IHC (paraffin) (verif.), WB (verif.) |
Conjugate: | No |
Format: | Purified, BSA-free |
Database Information
Handling & Safety
Storage: | +4°C |
Shipping: | +20°C (International: °C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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