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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| ATA-HPA036739.25 | 25 µl | - |
7 - 10 business days* |
335.00€
|
|||
| ATA-HPA036739.100 | 100 µl | - |
7 - 10 business days* |
446.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Required for DNA replication. Plays a role in the rescue of stalled replication... more
Product information "Anti-TOPBP1"
Protein function: Required for DNA replication. Plays a role in the rescue of stalled replication forks and checkpoint control. Binds double-stranded DNA breaks and nicks as well as single-stranded DNA. Recruits the SWI/SNF chromatin remodeling complex to E2F1-responsive promoters. Down-regulates E2F1 activity and inhibits E2F1-dependent apoptosis during G1/S transition and after DNA damage. Induces a large increase in the kinase activity of ATR (PubMed:16530042). [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 72% and to rat: 73%
| Keywords: | Anti-TopBP1, Anti-TOPBP1, Anti-KIAA0259, Anti-DNA topoisomerase 2-binding protein 1, Anti-DNA topoisomerase II-binding protein 1, Anti-DNA topoisomerase II-beta-binding protein 1 |
| Supplier: | Atlas Antibodies |
| Supplier-Nr: | HPA036739 |
Properties
| Application: | ICC |
| Antibody Type: | Polyclonal |
| Conjugate: | No |
| Host: | Rabbit |
| Species reactivity: | human |
| Immunogen: | Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: TVPDVNTEPS QNEQIIWDDP TAREERARLA SNLQWPSCPT QYSELQVDIQ NLEDSPFQKP LHDSEIAKQA VCDPGNIRVT EAPKHPISEE LETP (ATA-APrEST90838) |
Database Information
| KEGG ID : | K10728 | Matching products |
| UniProt ID : | Q92547 | Matching products |
| Gene ID | GeneID 11073 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +20°C (International: +20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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You will get a certificate here
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