Anti-Tollip, clone k1B17

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG56967.50	50 µl		-	-	6 - 14 business days*		488.00€

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Protein function: Component of the signaling pathway of IL-1 and Toll-like receptors. Inhibits... more

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Product information "Anti-Tollip, clone k1B17"

Protein function: Component of the signaling pathway of IL-1 and Toll-like receptors. Inhibits cell activation by microbial products. Recruits IRAK1 to the IL-1 receptor complex. Inhibits IRAK1 phosphorylation and kinase activity (PubMed:11751856). Connects the ubiquitin pathway to autophagy by functioning as a ubiquitin- ATG8 family adapter and thus mediating autophagic clearance of ubiquitin conjugates. The TOLLIP-dependent selective autophagy pathway plays an important role in clearance of cytotoxic polyQ proteins aggregates (PubMed:25042851). [The UniProt Consortium]

Keywords:	Anti-TOLLIP, Anti-Toll-interacting protein
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG56967

Properties

Application:	WB, ICC, IF, FC
Antibody Type:	Monoclonal
Clone:	k1B17
Conjugate:	No
Host:	Mouse
Species reactivity:	human
Immunogen:	Recombinant fragment around aa. 61-274 of Human Tollip
Format:	Purified