Anti-TOLLIP

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA038622.25	25 µl		-		7 - 10 business days*		335.00€
ATA-HPA038622.100	100 µl		-		7 - 10 business days*		446.00€

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Protein function: Component of the signaling pathway of IL-1 and Toll-like receptors. Inhibits... more

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Product information "Anti-TOLLIP"

Protein function: Component of the signaling pathway of IL-1 and Toll-like receptors. Inhibits cell activation by microbial products. Recruits IRAK1 to the IL-1 receptor complex. Inhibits IRAK1 phosphorylation and kinase activity (PubMed:11751856). Connects the ubiquitin pathway to autophagy by functioning as a ubiquitin-ATG8 family adapter and thus mediating autophagic clearance of ubiquitin conjugates. The TOLLIP- dependent selective autophagy pathway plays an important role in clearance of cytotoxic polyQ proteins aggregates (PubMed:25042851). [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 99% and to rat: 99%

Keywords:	Anti-TOLLIP, Anti-Toll-interacting protein
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA038622

Properties

Application:	IHC, WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, rat
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: VVQAKLAKNY GMTRMDPYCR LRLGYAVYET PTAHNGAKNP RWNKVIHCTV PPGVDSFYLE IFDERAFSMD DRIAWTHITI PES (ATA-APrEST80484)