Anti-Tollip

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG56416.100	100 µl		-	-	6 - 14 business days*		624.00€

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Protein function: Component of the signaling pathway of IL-1 and Toll-like receptors. Inhibits... more

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Product information "Anti-Tollip"

Protein function: Component of the signaling pathway of IL-1 and Toll-like receptors. Inhibits cell activation by microbial products. Recruits IRAK1 to the IL-1 receptor complex. Inhibits IRAK1 phosphorylation and kinase activity (PubMed:11751856). Connects the ubiquitin pathway to autophagy by functioning as a ubiquitin- ATG8 family adapter and thus mediating autophagic clearance of ubiquitin conjugates. The TOLLIP-dependent selective autophagy pathway plays an important role in clearance of cytotoxic polyQ proteins aggregates (PubMed:25042851). [The UniProt Consortium]

Keywords:	Anti-TOLLIP, Anti-Toll-interacting protein
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG56416

Properties

Application:	WB, IHC (paraffin), ICC, IF
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse (Expected: rat)
Immunogen:	Recombinant protein of Human Tollip
MW:	30 kD
Format:	Antigen Affinity Purified