Anti-Toca-1

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
A303-469A-T	10 µl (10 µg)		-		2 - 8 business days*		164.00€
A303-469A	100 µl (100 µg)		-		2 - 8 business days*		588.00€

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Protein function: Required to coordinate membrane tubulation with reorganization of the actin... more

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Product information "Anti-Toca-1"

Protein function: Required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during endocytosis. May bind to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promote membrane invagination and the formation of tubules. Also promotes CDC42-induced actin polymerization by activating the WASL/N-WASP-WASPIP/WIP complex, the predominant form of WASL/N-WASP in cells. Actin polymerization may promote the fission of membrane tubules to form endocytic vesicles. Essential for autophagy of intracellular bacterial pathogens. [The UniProt Consortium]

Keywords:	Anti-Toca-1, Anti-FNBP1L, Anti-C1orf39, Anti-Formin-binding protein 1-like, Anti-Transducer of Cdc42-dependent actin assembly protein 1
Supplier:	Bethyl Laboratories
Supplier-Nr:	A303-469A

Properties

Application:	WB, IP
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human (Expected: mouse, rat)
Immunogen:	synthetic peptide. The epitope recognized by A303-469A-T maps to a region between residue 50 and 100 of human Transducer of Cdc42-Dependent Actin Assembly Protein 1 using the numbering given in entry NP_001157945.1 (GeneID 54874).
Format:	Antigen Affinity Purified