Anti-TNKS2

Anti-TNKS2
Item number Size Datasheet Manual SDS Delivery time Quantity Price
G-CAB16575.50 50 µl - -

9 - 20 business days*

352.00€
G-CAB16575.100 100 µl -

9 - 20 business days*

448.00€
 
WB 1:500 - 1:2000. Protein function: Poly-ADP-ribosyltransferase involved in various processes... more
Product information "Anti-TNKS2"
WB 1:500 - 1:2000. Protein function: Poly-ADP-ribosyltransferase involved in various processes such as Wnt signaling pathway, telomere length and vesicle trafficking (PubMed:11739745, PubMed:11802774, PubMed:19759537, PubMed:21478859, PubMed:23622245, PubMed:25043379). Acts as an activator of the Wnt signaling pathway by mediating poly-ADP-ribosylation of AXIN1 and AXIN2, 2 key components of the beta-catenin destruction complex: poly-ADP- ribosylated target proteins are recognized by RNF146, which mediates their ubiquitination and subsequent degradation (PubMed:19759537, PubMed:21478859). Also mediates poly-ADP- ribosylation of BLZF1 and CASC3, followed by recruitment of RNF146 and subsequent ubiquitination (PubMed:21478859). Mediates poly- ADP-ribosylation of TERF1, thereby contributing to the regulation of telomere length (PubMed:11739745). Stimulates 26S proteasome activity (PubMed:23622245). [The UniProt Consortium]
Keywords: Anti-ARTD6, Anti-TANK2, Anti-TNKS-2, Anti-Tankyrase-2, Anti-Tankyrase II, Anti-Tankyrase-like protein, Anti-Tankyrase-related protein, Anti-Poly [ADP-ribose] polymerase 5B, Anti-Poly [ADP-ribose] polymerase tankyrase-2, TNKS2 Polyclonal Antibody (CAB16575
Supplier: Assay Genie
Supplier-Nr: CAB16575

Properties

Application: WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: mouse, rat

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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