Anti-TNF alpha

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG23973.50	50 µg		-	-	6 - 14 business days*		576.00€

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Protein function: Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted... more

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Product information "Anti-TNF alpha"

Protein function: Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation. Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces GKAP42 protein degradation in adipocytes which is partially responsible for TNF-induced insulin resistance. [The UniProt Consortium]

Keywords:	Anti-TNF, Anti-TNFA
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG23973

Properties

Application:	ELISA, WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	bovine, cat, dolphin, dog, swine
Immunogen:	Recombinant Pig TNF alpha
MW:	25 kD
Format:	Antigen Affinity Purified