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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
NSJ-F54134-0.05ML | 50 µl | - | - |
3 - 10 business days* |
326.00€
|
||
NSJ-F54134-0.2ML | 200 µl | - | - |
3 - 10 business days* |
702.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
In 1X PBS, pH 7.4, with 0.09% sodium azide. Involved in dendrite morphogenesis and maintenance by... more
Product information "Anti-TMEM106B (C-Terminal Region)"
In 1X PBS, pH 7.4, with 0.09% sodium azide. Involved in dendrite morphogenesis and maintenance by regulating lysosomal trafficking via its interaction with MAP6. May act by inhibiting retrograde transport of lysosomes along dendrites. Required for dendrite branching. [UniProt] Protein function: In neurons, involved in the transport of late endosomes/lysosomes (PubMed:25066864). May be involved in dendrite morphogenesis and maintenance by regulating lysosomal trafficking (PubMed:25066864). May act as a molecular brake for retrograde transport of late endosomes/lysosomes, possibly via its interaction with MAP6. In motoneurons, may mediate the axonal transport of lysosomes and axonal sorting at the initial segment. It remains unclear whether TMEM106B affects the transport of moving lysosomes in the anterograde or retrograde direction in neurites and whether it is important in the sorting of lysosomes in axons or in dendrites. In neurons, may also play a role in the regulation of lysosomal size and responsiveness to stress (PubMed:25066864). Required for proper lysosomal acidification. [The UniProt Consortium]
Keywords: | Anti-Transmembrane protein 106B, TMEM106B Antibody (C-Terminal Region) |
Supplier: | NSJ Bioreagents |
Supplier-Nr: | F54134 |
Properties
Application: | WB |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | mouse |
Immunogen: | A portion of amino acids 218-252 from human TMEM106B |
Format: | Purified |
Database Information
KEGG ID : | K25048 | Matching products |
UniProt ID : | Q9NUM4 | Matching products |
Gene ID | GeneID 54664 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | -20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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