Anti-TLR5

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
600-401-FG1	100 µg		-	-	6 - 10 business days*		684.00€

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Anti-TLR5 Antibody was affinity purified from monospecific antiserum by immunoaffinity... more

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Product information "Anti-TLR5"

Anti-TLR5 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with TLR5 from other sources has not been determined. Protein function: Functions as sorting adapter in LPS-TLR4 signaling to regulate the MYD88-independent pathway during the innate immune response to LPS. Physically bridges TLR4 and TICAM1 and functionally transmits LPS-TRL4 signal to TICAM1, signaling is proposed to occur in early endosomes after endocytosis of TLR4. May also be involved in IL1-triggered NF-kappa-B activation, functioning upstream of IRAK1, IRAK2, TRAF6, and IKBKB, however, reports are controversial. Involved in IL-18 signaling and is proposed to function as a sorting adaptor for MYD88 in IL-18 signaling during adaptive immune response. [The UniProt Consortium]

Keywords:	Anti-TICAM2, Anti-TIRAP3, Anti-MyD88-4, Anti-TICAM-2, Anti-TRIF-related adapter molecule, Anti-Toll-like receptor adaptor protein 3, Anti-TIR domain-containing adapter molecule 2, Anti-Putative NF-kappa-B-activating protein 502, Anti-Toll/interleukin-1 re
Supplier:	Rockland Immunochemicals
Supplier-Nr:	600-401-FG1

Properties

Application:	ELISA, IHC, WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse, rat
Immunogen:	Peptide corresponding to 16 amino acids near the internal region of human TLR5.
Format:	Purified