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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
NSJ-RQ7507 | 100 µg | - | - |
3 - 10 business days* |
755.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Enables ferritin receptor activity. Acts... more
Product information "Anti-Timd2 / T-cell immunoglobulin mucin receptor 2"
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Enables ferritin receptor activity. Acts upstream of or within iron ion transport. Located in cell surface. Is expressed in 4-cell stage embryo, liver, liver left lobe, liver right lobe, and metanephros. Human ortholog(s) of this gene implicated in atopic dermatitis. Orthologous to human HAVCR1 (hepatitis A virus cellular receptor 1). Protein function: Cell surface glycoprotein that participates in iron homeostasis in the liver, the kidney, the retina and oligodendrocytes by acting as a receptor of H-ferritin (PubMed:16203866, PubMed:33065090). Mechanistically, mediates iron-containing ferritin uptake via an endocytic pathway, trafficking to endosomes and subsequently to lysosomes (PubMed:16043519, PubMed:21886823). Plays also an important role in the regulation of Th2 immunity (PubMed:16043519). Receptor for SEMA4A involved in the regulation of T- cell function, enhancing T-cell activation (PubMed:12374982). [The UniProt Consortium]
Keywords: | Anti-Tim2, Anti-Timd2, Anti-TIM-2, Anti-TIMD-2, Anti-T-cell membrane protein 2, Anti-T-cell immunoglobulin mucin receptor 2, Anti-T-cell immunoglobulin and mucin domain-containing protein 2, Timd2 Antibody / T-cell immunoglobulin mucin receptor 2 |
Supplier: | NSJ Bioreagents |
Supplier-Nr: | RQ7507 |
Properties
Application: | WB, IHC (paraffin), FC, IF |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | mouse, rat |
Immunogen: | Amino acids KKVVERTRCEDQVYIIEDTPYPEE from the mouse protein |
Format: | Purified |
Database Information
KEGG ID : | K20413 | Matching products |
UniProt ID : | Q8R183 | Matching products |
Gene ID | GeneID 171284 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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