Anti-TIEG2

Anti-TIEG2
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ELK-ES3606.50 50 µl - -

Request delivery time estimate

169.00€
ELK-ES3606.100 100 µl - -

Request delivery time estimate

283.00€
 
The protein encoded by this gene is a zinc finger transcription factor that binds to SP1-like... more
Product information "Anti-TIEG2"
The protein encoded by this gene is a zinc finger transcription factor that binds to SP1-like sequences in epsilon- and gamma-globin gene promoters. This binding inhibits cell growth and causes apoptosis. Defects in this gene are a cause of maturity-onset diabetes of the young type 7 (MODY7). Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Apr 2010], Protein function: Transcription factor (PubMed:9748269, PubMed:10207080). Activates the epsilon- and gamma-globin gene promoters and, to a much lower degree, the beta-globin gene and represses promoters containing SP1-like binding inhibiting cell growth (PubMed:9748269, PubMed:10207080, PubMed:16131492). Represses transcription of SMAD7 which enhances TGF-beta signaling. Induces apoptosis. [The UniProt Consortium] Recommended dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.. Cellular localization: Nucleus .
Keywords: Anti-FKLF, Anti-KLF11, Anti-TIEG-2, Anti-Krueppel-like factor 11, Anti-TGFB-inducible early growth response protein 2, Anti-Transforming growth factor-beta-inducible early growth response protein 2, TIEG2 rabbit pAb
Supplier: ELK Biotechnology
Supplier-Nr: ES3606

Properties

Application: WB, IHC, IF, ELISA
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse
Immunogen: The antiserum was produced against synthesized peptide derived from human KLF11. AA range:1-50
MW: 55 kD
Format: Antiserum

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow. more
You will get a certificate here
or to request a certificate of analysis.
Read, write and discuss reviews... more
Customer review for "Anti-TIEG2"
Write a review
or to review a product.
Viewed